Given its pharmacological similarities to LSD, and its likely function as a prodrug of it, 1P-LSD is likely to trigger relevant drug tests in exactly the same way. However, LSD tends not to be included in standard drug tests and is only sometimes tested for in extended screens. As with LSD, excretion through urine reaches a peak about 4 to 6 hours after administering a dose in humans, but even then, the amounts are quite small. There are four known major metabolites of LSD in humans that are excreted and can be detected in urine for up to 4 to 5 days after ingestion, with observed inter-individual variation. There are several criteria that determine how long LSD can be detected in the body: the test being used; the detection limit placed on the test; the point of collection; the type of sample fluid; the amount that was ingested.
The average time LSD can be detected in blood is 6-12 hours and in urine is 2-4 days. However, one metabolite (2-oxo-3-hydroxy-LSD) is typically present in higher concentrations and can be detected for longer periods of time in urine.
Tests for LSD (but not its metabolites) in hair samples are also available and they’re good for detecting both low doses and single uses, apparently for an underdetermined but long period of time after dosing.